819+ Vacation Rentals & Holiday Homes in Santo Domingo Este |
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Santo Domingo Este Accommodations - Hotels & Rentals

About Santo Domingo Este Vacation Rentals

Discover More than 819 Incredible Getaway Rentals Available in Santo Domingo Este. Choose from a Wide Selection of Villas, Hotels, and Other Rental Options. Explore Luxury Amenities at Affordable Prices, Creating the Ideal Base for Your Next Vacation. Plan Your Perfect Escape with Online Reservations and Uncover Fantastic Stays in Santo Domingo Este.

Online Reservations Offers Numerous Last-Minute Deals on Villas, Hotels, and Rentals, Both Near You and Across the Globe. Whether You Need Accommodation for a Group or an Event, Be it a Hotel or Vacation Rental (Including Cabins and Private Luxury Villas), We're Here to Assist. With Online Reservations in Santo Domingo Este, You Can Easily Compare Options from Multiple Suppliers with a Single Click to Find the Perfect Price Point, Amenities, and Style of Stay That Suit Your Needs. Looking for Group Deals, Properties with Private Pools, Hot Tubs, Pet-Friendly Options, or Spacious Master Suite Bedrooms with Open-Air Showers? You Can Find It All in the Online Reservations Vacation Rentals, Resorts, and Airbnb-Style Properties in Santo Domingo Este. The Average Size of Places to Stay Near Santo Domingo Este is 479.25 ft², with Prices Averaging US $78 per Night.

Let Online Reservations Help You Discover the Ideal Holiday Rental to Create Lifelong Travel Memories in Santo Domingo Este. Our Listed Prices Are Often Discounted Compared to Rack Rates. Simply Search for Your Destination and Secure the Perfect Place to Stay Today.

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Top Hotels & Vacation Rentals in Santo Domingo Este

Type Count
Holiday Apartments 641
Vacation Homes 96
Villas 26
Cottages 1

Use these Quick Filters to Find a Vacation Rental in Santo Domingo Este

★ Pro Tip: Online Reservations is a vacation rental website specializing in cottages, lake houses, and exclusive summer home rentals. We curate a vast selection of incredible properties from trusted suppliers, allowing you to compare prices and locations to find the perfect fit for your getaway. Create lasting memories in Santo Domingo Este with Online Reservations.

Activities Santo Domingo EsteGuest Reviews Local Attractions

A Large Selection of Hotels and Vacation Rentals from Around the World Santo Domingo EsteGuest Reviews Discover Exciting Activities and Must-Visit Destinations for Your Upcoming Journey


Assembly Hall of Jehovah's Witnesses
Agua Splash Caribe Parque Acuatico
Megacentro Mall
National Aquarium
Colon Lighthouse and Museum
Agua Splash Caribe Aquatic Park
Zona Franca de San Isidro Industrial Area
Coral Mall
Three Eyes Park
El Obelisco
Boca Chica
Blue Mall
Sambil Santo Domingo
Coral Hamaca Resort
Guibia Beach
Parque Colon
Agora Mall
Dream Casino Be Live Hamaca
Cathedral of Santo Domingo
Guayacanes Beach

Find Hotels & Vacation Rentals in these Cities and Neighborhoods


Barrio La Isabelita 1,059 Properties
Residencial del Este 759 Properties
Vista Hermosa 316 Properties
Corales del Sur 172 Properties
Ensanche Ozama 155 Properties
La Isabelita 84 Properties
Ensanche Isabelita 79 Properties
Mendoza 64 Properties
Los Frailes 41 Properties
Prado Oriental 36 Properties
Alma Rosa 27 Properties
Tropical del Este 25 Properties

Frequently Asked Questions About Santo Domingo Este?

What are the top hotels, lake houses & vacation rentals in Santo Domingo Este?

We provide an array of great vacation destinations in Santo Domingo Este. If you are looking to stay in or around the Santo Domingo Este area, make sure to browse our options to find a premium rental location in a top vacation destination. Whether it is a few nights, a week, or more, we've got the luxury stays that rank among the Top Vacation Rentals in Santo Domingo Este:

How many Hotels & Vacation Rentals have private pools in Santo Domingo Este?

We have 25 Hotels & Vacation Rentals featuring a private pool in and near Santo Domingo Este. Some of the best destinations to stay that feature or have access to a swimming pool are:

Which hotel, lake house, or vacation rental in Santo Domingo Este is best for families?

Searching for a family-friendly getaway in Santo Domingo Este? We've got you covered. Check out one of these luxurious getaways that are highly-rated and perfect fits for families of all sizes.

How many hotels, resorts, or rentals are available in Santo Domingo Este?

Online Reservations™ offers a consistent supply of new options, combined with established great stays in top areas. Currently, the number of properties listed by Online Reservations™ in 2025 is over 819 in the Santo Domingo Este area, and that number rises every day. By combining listings from multiple websites and travel providers, Online Reservations™ can provide you with a diverse amount of choices of the best luxury stays in Santo Domingo Este.

Nearby Neighborhood (11) 
Neighborhood Property Count
Zona Colonial Vacation Rentals in Santo Domingo, Santo Domingo 509
Corales del Sur Vacation Rentals in Santo Domingo, Santo Domingo 172
Ensanche Isabelita Vacation Rentals in Santo Domingo, Santo Domingo 79
Prado Oriental Vacation Rentals in Santo Domingo, Santo Domingo 36
Tropical del Este Vacation Rentals in Santo Domingo, Santo Domingo 25
Barrio La Isabelita Vacation Rentals in Santo Domingo, Santo Domingo 1059
Vista Hermosa Vacation Rentals in Santo Domingo, Santo Domingo 316
Residencial del Este Vacation Rentals in Santo Domingo, Santo Domingo 759
Maquiteria Vacation Rentals in Santo Domingo, Santo Domingo 1281
Los Coquitos Vacation Rentals in Santo Domingo, Santo Domingo 1211
Riviera Del Caribe Vacation Rentals in Santo Domingo, Santo Domingo 106

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